What are the best ways to farm Endo in Warframe?

The two most efficient Endo sources in Warframe today are Arbitrations and the Vodyanoi arena on Sedna. Guided by recent breakdowns, Arbitrations average around 11,796 Endo per hour when you include Ayatan Sculptures after filling them, while the Vodynai/Sedna arena can exceed 10,000 Endo per hour with a coordinated four-player squad and the right loot setup. For players just starting to hunt Endo, these are the intake points that scale with time and team effort. TheGamer: How To Farm Endo Quickly In Warframe; Dot Esports: Best ways to farm Endo in Warframe (2024)

If you’re chasing maximum efficiency from Arbitrations, go in with a solid four-player squad and leverage loot modifiers (drop boosters) to push Endo and Ayatan Sculptures drops. Nekros’ Desecrate and Khora’s Pilfering Strangledome are popularly cited as boosting Endo yields in Vodyanoi runs, and similar stacking setups can improve Arbitration loot as well. TheGamer: Endo Farm guide

Beyond these top farms, you can add steady, reliable sources: dissolving duplicate mods in your Orbiter converts duplicates into Endo (5–20 Endo per item, depending on rarity), Ayatan Sculptures can be filled and traded for Endo at Maroo’s Bazaar, and Ayatan Weeklies can yield up to about 2,700 Endo per week. Railjack and high-level Excavation missions (e.g., Cholistan, Despina, Hieracon) provide tens of thousands more Endo over time, especially with coordinated teams. TheGamer: Endo Farm guide; Warframe Wiki: Endo; Warframe School: Arbitrations Guide